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    Afatinib (BIBW 2992; Tovok)

    Afatinib (BIBW 2992; Tovok)

    Synonym

    (S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide

    Molecular Formula

    C24H25ClFN5O3

    Molecular Weight

    485.95

    Catalogue Number

    AR-A01477

    Parent Drug

    AFATINIB

    CAS Number

    850140-72-6

    Common Package:10,25,50,100 mg

    Collections: AFATINIB

    Category: 850140-72-6 AFATINIB AR-A01477 C24H25ClFN5O3

    RELATED PRODUCTS
    (S,E)-2-((3-chloro-4-fluorophenyl)(6-(4-(dimethylamino)but-2-enamido)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-yl)amino)malonic acid

    Synonym

    (S,E)-2-((3-chloro-4-fluorophenyl)(6-(4-(dimethylamino)but-2-enamido)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-yl)amino)malonic acid

    Molecular Formula

    C27H27ClFN5O7

    Molecular Weight

    587.99

    Catalogue Number

    AR-A01512

    Parent Drug

    AFATINIB
    (S)-N4-(3,4-difluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine

    Synonym

    (S)-N4-(3,4-difluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine

    Molecular Formula

    C18H16F2N4O2

    Molecular Weight

    358.35

    Catalogue Number

    AR-A01511

    Parent Drug

    AFATINIB

    CAS Number

    2044709-72-8
    (E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-ethoxyquinazolin-6-yl)-4-(dimethylamino)but-2-enamide

    Synonym

    (E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-ethoxyquinazolin-6-yl)-4-(dimethylamino)but-2-enamide

    Molecular Formula

    C22H23ClFN5O2

    Molecular Weight

    443.91

    Catalogue Number

    AR-A01510

    Parent Drug

    AFATINIB
    (E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-4-(dimethylamino)but-2-enamide

    Synonym

    (E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-4-(dimethylamino)but-2-enamide

    Molecular Formula

    C21H21ClFN5O2

    Molecular Weight

    429.89

    Catalogue Number

    AR-A01509

    Parent Drug

    AFATINIB
    (S,E)-4-(dimethylamino)-N-(4-((4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide

    Synonym

    (S,E)-4-(dimethylamino)-N-(4-((4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide

    Molecular Formula

    C24H26FN5O3

    Molecular Weight

    451.50

    Catalogue Number

    AR-A01508

    Parent Drug

    AFATINIB
    (S)-N-(((4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)amino)methylene)-N-methylmethanaminium

    Synonym

    (S)-N-(((4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)amino)methylene)-N-methylmethanaminium

    Molecular Formula

    C21H22ClFN5O2

    Molecular Weight

    430.89

    Catalogue Number

    AR-A01507

    Parent Drug

    AFATINIB
    (S)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)formamide

    Synonym

    (S)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)formamide

    Molecular Formula

    C19H16ClFN4O3

    Molecular Weight

    402.82

    Catalogue Number

    AR-A01506

    Parent Drug

    AFATINIB
    (R)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-(((R)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)-3-hydroxybutanamide

    Synonym

    (R)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-(((R)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)-3-hydroxybutanamide

    Molecular Formula

    C24H27ClFN5O4

    Molecular Weight

    503.97

    Catalogue Number

    AR-A01505

    Parent Drug

    AFATINIB
    (S)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-(((R)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)-3-hydroxybutanamide

    Synonym

    (S)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-(((R)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)-3-hydroxybutanamide

    Molecular Formula

    C24H27ClFN5O4

    Molecular Weight

    503.97

    Catalogue Number

    AR-A01504

    Parent Drug

    AFATINIB
    1-(4-((3-chloro-4-fluorophenyl)amino)-7-(((R)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-5-hydroxypyrrolidin-2-one

    Synonym

    1-(4-((3-chloro-4-fluorophenyl)amino)-7-(((R)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-5-hydroxypyrrolidin-2-one

    Molecular Formula

    C22H20ClFN4O4

    Molecular Weight

    458.88

    Catalogue Number

    AR-A01503

    Parent Drug

    AFATINIB
    (S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-hydroxybut-2-enamide

    Synonym

    (S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-hydroxybut-2-enamide

    Molecular Formula

    C22H20ClFN4O4

    Molecular Weight

    458.87

    Catalogue Number

    AR-A01502

    Parent Drug

    AFATINIB
    (S)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-3-enamide

    Synonym

    (S)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-3-enamide

    Molecular Formula

    C22H20ClFN4O3

    Molecular Weight

    442.88

    Catalogue Number

    AR-A01501

    Parent Drug

    AFATINIB
    Afatinib Impurity L (Afatinib N-Oxide)

    Synonym

    (S,E)-4-((4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)amino)-N,N-dimethyl-4-oxobut-2-en-1-amine oxide

    Molecular Formula

    C24H25ClFN5O4

    Molecular Weight

    501.95

    Catalogue Number

    AR-A01500

    Parent Drug

    AFATINIB
    (E)-N-(4-((3-chloro-4-fluorophenyl)(4-((4-((3-chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)amino)-1-(dimethylamino)-4-oxobutan-2-yl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide

    Synonym

    (E)-N-(4-((3-chloro-4-fluorophenyl)(4-((4-((3-chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)amino)-1-(dimethylamino)-4-oxobutan-2-yl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide

    Molecular Formula

    C48H50Cl2F2N10O6

    Molecular Weight

    971.90

    Catalogue Number

    AR-A01499

    Parent Drug

    AFATINIB
    3-((3-chloro-4-fluorophenyl)(6-((E)-4-(dimethylamino)but-2-enamido)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-4-yl)amino)-4-(dimethylamino)butanoic acid

    Synonym

    3-((3-chloro-4-fluorophenyl)(6-((E)-4-(dimethylamino)but-2-enamido)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-4-yl)amino)-4-(dimethylamino)butanoic acid

    Molecular Formula

    C30H36ClFN6O5

    Molecular Weight

    615.11

    Catalogue Number

    AR-A01498

    Parent Drug

    AFATINIB
    (S)-N4-(3-chlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine

    Synonym

    (S)-N4-(3-chlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine

    Molecular Formula

    C18H17ClN4O2

    Molecular Weight

    356.81

    Catalogue Number

    AR-A01497

    Parent Drug

    AFATINIB
    (S)-N4-phenyl-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine

    Synonym

    (S)-N4-phenyl-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine

    Molecular Formula

    C18H18N4O2

    Molecular Weight

    322.37

    Catalogue Number

    AR-A01496

    Parent Drug

    AFATINIB
    (S)-N4-(4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine

    Synonym

    (S)-N4-(4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine

    Molecular Formula

    C18H17FN4O2

    Molecular Weight

    340.36

    Catalogue Number

    AR-A01495

    Parent Drug

    AFATINIB
    N-(3,5,7-trimethyladamantan-1-yl)acetamide

    Synonym

    N-(3-chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine

    Molecular Formula

    C15H10ClFN4O3

    Molecular Weight

    348.72

    Catalogue Number

    AR-A01494

    Parent Drug

    AFATINIB

    CAS Number

    179552-74-0
    N-(3,4-dichlorophenyl)-7-fluoro-6-nitroquinazolin-4-amine

    Synonym

    N-(3,4-dichlorophenyl)-7-fluoro-6-nitroquinazolin-4-amine

    Molecular Formula

    C14H7Cl2FN4O2

    Molecular Weight

    353.14

    Catalogue Number

    AR-A01493

    Parent Drug

    AFATINIB
    Afatinib Impurity K

    Synonym

    (S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(methylamino)but-2-enamide

    Molecular Formula

    C23H23ClFN5O3

    Molecular Weight

    471.92

    Catalogue Number

    AR-A01492

    Parent Drug

    AFATINIB
    Afatinib Impurity J HCl

    Synonym

    (S,E)-4-(dimethylamino)-N-(4-hydroxy-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide hydrochloride

    Molecular Formula

    C18H22N4O4. HCl

    Molecular Weight

    358.40 36.46

    Catalogue Number

    AR-A01491

    Parent Drug

    AFATINIB

    CAS Number

    1456696-14-2 (keto form)
    Afatinib Impurity I

    Synonym

    (S,E)-4-bromo-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide

    Molecular Formula

    C22H19BrClFN4O3

    Molecular Weight

    521.78

    Catalogue Number

    AR-A01490

    Parent Drug

    AFATINIB

    CAS Number

    N/A
    Afatinib Impurity H

    Synonym

    (S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide

    Molecular Formula

    C22H20ClFN4O3

    Molecular Weight

    442.88

    Catalogue Number

    AR-A01489

    Parent Drug

    AFATINIB

    CAS Number

    N/A
    Afatinib Impurity G

    Synonym

    (S,E)-N-(4-((4-chloro-3-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide

    Molecular Formula

    C24H25ClFN5O3

    Molecular Weight

    485.95

    Catalogue Number

    AR-A01488

    Parent Drug

    AFATINIB

    CAS Number

    N/A
    Afatinib Impurity F

    Synonym

    (S,E)-N-(4-((3,4-difluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide

    Molecular Formula

    C24H25F2N5O3

    Molecular Weight

    469.50

    Catalogue Number

    AR-A01487

    Parent Drug

    AFATINIB

    CAS Number

    N/A
    Afatinib Impurity E

    Synonym

    (S,E)-N-(4-((3,4-dichlorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide

    Molecular Formula

    C24H25Cl2N5O3

    Molecular Weight

    502.40

    Catalogue Number

    AR-A01486

    Parent Drug

    AFATINIB

    CAS Number

    N/A
    Afatinib Impurity D (Z-Afatinib)

    Synonym

    (S,Z)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide

    Molecular Formula

    C24H25ClFN5O3

    Molecular Weight

    485.95

    Catalogue Number

    AR-A01485

    Parent Drug

    AFATINIB

    CAS Number

    N/A
    Afatinib Impurity C

    Synonym

    (R,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide

    Molecular Formula

    C24H25ClFN5O3

    Molecular Weight

    485.94

    Catalogue Number

    AR-A01484

    Parent Drug

    AFATINIB

    CAS Number

    945553-91-3
    4-((4-chloro-3-fluorophenyl)amino)-6-nitroquinazolin-7-ol

    Synonym

    4-((4-chloro-3-fluorophenyl)amino)-6-nitroquinazolin-7-ol

    Molecular Formula

    C14H8ClFN4O3

    Molecular Weight

    334.70

    Catalogue Number

    AR-A01483

    Parent Drug

    AFATINIB
    N-(4-chloro-3-fluorophenyl)-7-fluoro-8-nitroquinazolin-4-amine

    Synonym

    N-(4-chloro-3-fluorophenyl)-7-fluoro-8-nitroquinazolin-4-amine

    Molecular Formula

    C14H7ClF2N4O2

    Molecular Weight

    336.69

    Catalogue Number

    AR-A01482

    Parent Drug

    AFATINIB
    Afatinib-d6

    Synonym

    (E)-4-[bis(trideuteriomethyl)amino]-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]but-2-enamide

    Molecular Formula

    C24H19ClFN5O3D6

    Molecular Weight

    491.99

    Catalogue Number

    AR-A01481

    Parent Drug

    AFATINIB

    CAS Number

    1313874-96-2
    Afatinib Impurity B

    Synonym

    (S)-N4-(3-chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine

    Molecular Formula

    C18H16ClFN4O2

    Molecular Weight

    374.81

    Catalogue Number

    AR-A01480

    Parent Drug

    AFATINIB

    CAS Number

    314771-76-1
    Afatinib Impurity A

    Synonym

    (S)-N-(3-chloro-4-fluorophenyl)-6-nitro-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-amine

    Molecular Formula

    C18H14ClFN4O4

    Molecular Weight

    404.79

    Catalogue Number

    AR-A01479

    Parent Drug

    AFATINIB

    CAS Number

    N/A
    Afatinib-d4

    Synonym

    (S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide-D4

    Molecular Formula

    C24H21ClFN5O3D4

    Molecular Weight

    489.97

    Catalogue Number

    AR-A01478

    Parent Drug

    AFATINIB

    CAS Number

    850140-72-6(non-d)