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    Regorafenib N-Oxide (M2 Metabolite)

    Regorafenib N-Oxide (M2 Metabolite)

    Synonym

    4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-2-(methylcarbamoyl)pyridine 1-oxide

    Molecular Formula

    C21H15ClF4N4O4

    Molecular Weight

    498.82

    Catalogue Number

    AR-R01319

    Parent Drug

    REGORAFENIB

    CAS Number

    835621-11-9

    Common Package:10,25,50,100 mg

    Collections: REGORAFENIB

    Category: 835621-11-9 AR-R01319 C21H15ClF4N4O4 REGORAFENIB

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    4,6-dichloro-N-methylpicolinamide

    Synonym

    4,6-dichloro-N-methylpicolinamide

    Molecular Formula

    C7H6Cl2N2O

    Molecular Weight

    205.04

    Catalogue Number

    AR-R01333

    Parent Drug

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    4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)phenoxy)phenoxy)-N-methylpicolinamide

    Synonym

    4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)phenoxy)phenoxy)-N-methylpicolinamide

    Molecular Formula

    C49H31Cl3F10N8O7

    Molecular Weight

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    4,4'-((2-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)azanediyl)bis(N-methylpicolinamide)

    Synonym

    4,4'-((2-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)azanediyl)bis(N-methylpicolinamide)

    Molecular Formula

    C27H24FN7O4

    Molecular Weight

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    Catalogue Number

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    N-Desmethyl Regorafenib-d3

    Synonym

    4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)picolinamide-D3

    Molecular Formula

    C20H10D3ClF4N4O3

    Molecular Weight

    471.81

    Catalogue Number

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    CAS Number

    1343498-72-5 (non-labelled)
    4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)phenoxy)-N-methylpicolinamide

    Synonym

    4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)phenoxy)-N-methylpicolinamide

    Molecular Formula

    C35H23Cl2F7N6O5

    Molecular Weight

    811.49

    Catalogue Number

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    N-Desmethyl Regorafenib

    Synonym

    4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)picolinamide

    Molecular Formula

    C20H13ClF4N4O3

    Molecular Weight

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    (R)-3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-1-one hydrochloride

    Synonym

    4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)picolinic acid

    Molecular Formula

    C20H12ClF4N3O4

    Molecular Weight

    469.78

    Catalogue Number

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    Parent Drug

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    CAS Number

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    4,4'-(((carbonylbis(azanediyl))bis(3-fluoro-4,1-phenylene))bis(oxy))bis(N-methylpicolinamide)

    Synonym

    4,4'-(((carbonylbis(azanediyl))bis(3-fluoro-4,1-phenylene))bis(oxy))bis(N-methylpicolinamide)

    Molecular Formula

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    Molecular Weight

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    4-(3-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)amino)phenoxy)-N-methylpicolinamide

    Synonym

    4-(3-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)amino)phenoxy)-N-methylpicolinamide

    Molecular Formula

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    Molecular Weight

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    4-(4-(3-(2-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide

    Synonym

    4-(4-(3-(2-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide

    Molecular Formula

    C21H15ClF4N4O3

    Molecular Weight

    482.83

    Catalogue Number

    AR-R01324

    Parent Drug

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    4-(3-fluoro-4-(3-(3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamide

    Synonym

    4-(3-fluoro-4-(3-(3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamide

    Molecular Formula

    C21H16F4N4O3

    Molecular Weight

    448.38

    Catalogue Number

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    Parent Drug

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    Hydroxyregorafenib

    Synonym

    4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-(hydroxymethyl)picolinamide

    Molecular Formula

    C21H15ClF4N4O4

    Molecular Weight

    498.82

    Catalogue Number

    AR-R01322

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    CAS Number

    N/A
    Regorafenib N-Oxide N-Glucuronide

    Synonym

    4-(4-(3-((2R,3R,4S,5S,6S)-6-carboxy-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)-3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-2-(methylcarbamoyl)pyridine 1-oxide

    Molecular Formula

    C27H23ClF4N4O10

    Molecular Weight

    647.95

    Catalogue Number

    AR-R01321

    Parent Drug

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    CAS Number

    N/A
    N-Desmethyl Regorafenib N-Oxide (M5 Metabolite)

    Synonym

    2-carbamoyl-4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)pyridine 1-oxide

    Molecular Formula

    C20H13ClF4N4O4

    Molecular Weight

    484.80

    Catalogue Number

    AR-R01320

    Parent Drug

    REGORAFENIB

    CAS Number

    835621-12-0
    Regorafenib-13C-d3 N-Glucuronide (M7 Metabolite)

    Synonym

    (2S,3S,4S,5R,6R)-6-(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(2-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)ureido)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid-13CD3

    Molecular Formula

    C27H20ClF4N4O9D3

    Molecular Weight

    662.96

    Catalogue Number

    AR-R01318

    Parent Drug

    REGORAFENIB

    CAS Number

    N/A
    Regorafenib N-Glucuronide (M7 Metabolite)

    Synonym

    (2S,3S,4S,5R,6R)-6-(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(2-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)ureido)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid

    Molecular Formula

    C27H23ClF4N4O9

    Molecular Weight

    658.95

    Catalogue Number

    AR-R01317

    Parent Drug

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    CAS Number

    N/A
    N-Desmethyl Regorafenib-d3 N-Oxide

    Synonym

    2-carbamoyl-4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)pyridine 1-oxide-D3

    Molecular Formula

    C20H10D3ClF4N4O4

    Molecular Weight

    487.81

    Catalogue Number

    AR-R01316

    Parent Drug

    REGORAFENIB

    CAS Number

    835621-12-0 (non-labelled)
    Regorafenib-13C-d3 N-Oxide

    Synonym

    4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-2-(methylcarbamoyl)pyridine 1-oxide-13CD3

    Molecular Formula

    13C C20H12D3ClF4N4O4

    Molecular Weight

    502.83

    Catalogue Number

    AR-R01315

    Parent Drug

    REGORAFENIB

    CAS Number

    835621-11-9 (non-labelled)
    4-(4-amino-3-fluorophenoxy)-N-(2-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)picolinamide

    Synonym

    4-(4-amino-3-fluorophenoxy)-N-(2-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)picolinamide

    Molecular Formula

    C25H19F2N5O4

    Molecular Weight

    491.46

    Catalogue Number

    AR-R01314

    Parent Drug

    REGORAFENIB
    Regorafenib-13C-d3

    Synonym

    4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide-13CD3

    Molecular Formula

    13C C20H12ClF4N4O3D3

    Molecular Weight

    486.83

    Catalogue Number

    AR-R01313

    Parent Drug

    REGORAFENIB

    CAS Number

    755037-03-7 (non-labelled)
    Regorafenib

    Synonym

    4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide

    Molecular Formula

    C21H15ClF4N4O3

    Molecular Weight

    482.83

    Catalogue Number

    AR-R01312

    Parent Drug

    REGORAFENIB

    CAS Number

    755037-03-7