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    Tofacitinib Impurity I

    Tofacitinib Impurity I

    Synonym

    (3S,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride

    Molecular Formula

    C14H22N2 2HCl

    Molecular Weight

    218.34 2x36.46

    Catalogue Number

    AR-T02444

    Parent Drug

    TOFACITINIB

    CAS Number

    N/A

    Common Package:10,25,50,100 mg

    Collections: TOFACITINIB

    Category: AR-T02444 C14H22N2 2HCl N/A TOFACITINIB

    RELATED PRODUCTS
    3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)propanenitrile

    Synonym

    3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)propanenitrile

    Molecular Formula

    C16H22N6

    Molecular Weight

    298.39

    Catalogue Number

    AR-T02507

    Parent Drug

    TOFACITINIB
    N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-[4,7'-bipyrrolo[2,3-d]pyrimidin]-4'-amine

    Synonym

    N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-[4,7'-bipyrrolo[2,3-d]pyrimidin]-4'-amine

    Molecular Formula

    C19H22N8

    Molecular Weight

    362.44

    Catalogue Number

    AR-T02506

    Parent Drug

    TOFACITINIB
    (3R,4R)-1-benzyl-4-methyl-3-(methylamino)piperidine 1-oxide dihydrochloride

    Synonym

    (3R,4R)-1-benzyl-4-methyl-3-(methylamino)piperidine 1-oxide dihydrochloride

    Molecular Formula

    C14H22N2O

    Molecular Weight

    234.34

    Catalogue Number

    AR-T02505

    Parent Drug

    TOFACITINIB
    N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-N-methylhydroxylamine dihydrochloride

    Synonym

    N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-N-methylhydroxylamine dihydrochloride

    Molecular Formula

    C14H22N2O

    Molecular Weight

    234.34

    Catalogue Number

    AR-T02504

    Parent Drug

    TOFACITINIB
    (E)-3-hydroxy-2-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine-1-carbonyl)pent-2-enedinitrile

    Synonym

    (E)-3-hydroxy-2-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine-1-carbonyl)pent-2-enedinitrile

    Molecular Formula

    C19H21N7O2

    Molecular Weight

    379.42

    Catalogue Number

    AR-T02503

    Parent Drug

    TOFACITINIB
    N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-2,2'-dichloro-N-methyl-7H-[4,7'-bipyrrolo[2,3-d]pyrimidin]-4'-amine

    Synonym

    N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-2,2'-dichloro-N-methyl-7H-[4,7'-bipyrrolo[2,3-d]pyrimidin]-4'-amine

    Molecular Formula

    C26H26Cl2N8

    Molecular Weight

    521.45

    Catalogue Number

    AR-T02502

    Parent Drug

    TOFACITINIB
    2-chloro-N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-amine

    Synonym

    2-chloro-N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-amine

    Molecular Formula

    C13H20ClN5

    Molecular Weight

    281.79

    Catalogue Number

    AR-T02501

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 49

    Molecular Formula

    C20H24ClN5

    Molecular Weight

    369.90

    Catalogue Number

    AR-T02500

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 48

    Molecular Formula

    C14H22N2. C20H18O8

    Molecular Weight

    218.34 386.36

    Catalogue Number

    AR-T02499

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 47

    Synonym

    (3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine (2S,3S)-2,3-bis((4-methylbenzoyl)oxy)succinate

    Molecular Formula

    C14H22N2. C20H18O8

    Molecular Weight

    218.34 386.36

    Catalogue Number

    AR-T02498

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 46

    Synonym

    (3S,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine (2S,3S)-2,3-bis((4-methylbenzoyl)oxy)succinate

    Molecular Formula

    C14H22N2. C20H18O8

    Molecular Weight

    218.34 386.36

    Catalogue Number

    AR-T02497

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 45

    Synonym

    N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-2-chloro-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

    Molecular Formula

    C20H24ClN5

    Molecular Weight

    369.90

    Catalogue Number

    AR-T02496

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 44

    Synonym

    (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine (2R,3R)-2,3-bis((4-methylbenzoyl)oxy)succinate

    Molecular Formula

    C14H22N2. C20H18O8

    Molecular Weight

    218.34 386.36

    Catalogue Number

    AR-T02495

    Parent Drug

    TOFACITINIB
    2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidine

    Synonym

    2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidine

    Molecular Formula

    C6H3Cl2N3

    Molecular Weight

    188.01

    Catalogue Number

    AR-T02494

    Parent Drug

    TOFACITINIB

    CAS Number

    90213-66-4
    DBU

    Synonym

    2,3,4,6,7,8,9,10-octahydropyrimido[1,2-a]azepine

    Molecular Formula

    C9H16N2

    Molecular Weight

    152.24

    Catalogue Number

    AR-T02493

    Parent Drug

    TOFACITINIB

    CAS Number

    6674-22-2
    Tofacitinib Related Compound 43

    Synonym

    ((1-benzyl-4-methylpiperidin-3-yl)amino)methanol

    Molecular Formula

    C14H22N2O

    Molecular Weight

    234.34

    Catalogue Number

    AR-T02492

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 42

    Synonym

    N-methyl-N-((3R,4R)-4-methyl-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

    Molecular Formula

    C19H22N8

    Molecular Weight

    362.44

    Catalogue Number

    AR-T02491

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 41

    Synonym

    (E)-tert-butyl 3-amino-2-cyano-5-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-5-oxopent-2-enoate

    Molecular Formula

    C23H31N7O3

    Molecular Weight

    453.55

    Catalogue Number

    AR-T02490

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 40

    Synonym

    tert-butyl 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanoate

    Molecular Formula

    C20H29N5O3

    Molecular Weight

    387.48

    Catalogue Number

    AR-T02489

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 39

    Synonym

    N-((3S,4S)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

    Molecular Formula

    C27H31N5O2S

    Molecular Weight

    489.64

    Catalogue Number

    AR-T02488

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 37

    Synonym

    2-((3S,4R)-3-((S)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)ethyl)-4-methylpiperidin-1-yl)-3-((3R,4R)-3-((7-(2-cyanoacetyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile

    Molecular Formula

    C33H41N11O2

    Molecular Weight

    623.77

    Catalogue Number

    AR-T02487

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 36

    Synonym

    3-ethoxy-3-hydroxy-2-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine-1-carbonyl)pentanedinitrile

    Molecular Formula

    C21H27N7O3

    Molecular Weight

    425.49

    Catalogue Number

    AR-T02486

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 35

    Synonym

    (E)-ethyl 3-amino-2-cyano-5-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-5-oxopent-2-enoate

    Molecular Formula

    C21H27N7O3

    Molecular Weight

    425.49

    Catalogue Number

    AR-T02485

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 34

    Synonym

    N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-2-chloro-N-methyl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-amine

    Molecular Formula

    C20H26ClN5

    Molecular Weight

    371.91

    Catalogue Number

    AR-T02484

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 32

    Synonym

    3-butoxy-3-hydroxy-2-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine-1-carbonyl)pentanedinitrile

    Molecular Formula

    C23H31N7O3

    Molecular Weight

    453.55

    Catalogue Number

    AR-T02483

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 31

    Synonym

    4'-chloro-7H-4,7'-bipyrrolo[2,3-d]pyrimidine

    Molecular Formula

    C12H7ClN6

    Molecular Weight

    270.68

    Catalogue Number

    AR-T02482

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 30

    Synonym

    N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-amine

    Molecular Formula

    C20H27N5

    Molecular Weight

    337.47

    Catalogue Number

    AR-T02481

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 29

    Synonym

    4-chloro-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine

    Molecular Formula

    C6H6ClN3

    Molecular Weight

    155.59

    Catalogue Number

    AR-T02480

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 33

    Synonym

    3-hydroxy-3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-2-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine-1-carbonyl)pentanedinitrile

    Molecular Formula

    C32H40N12O2

    Molecular Weight

    624.75

    Catalogue Number

    AR-T02479

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 28 (rac-trans-Tofacitinib)

    Molecular Formula

    C16H20N6O

    Molecular Weight

    312.38

    Catalogue Number

    AR-T02478

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 27

    Molecular Formula

    C13H18N4O2

    Molecular Weight

    262.31

    Catalogue Number

    AR-T02477

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 26 HCl

    Molecular Formula

    C10H17N3O. HCl

    Molecular Weight

    195.27 36.46

    Catalogue Number

    AR-T02476

    Parent Drug

    TOFACITINIB

    CAS Number

    1206824-85-2
    Tofacitinib Related Compound 25

    Synonym

    N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7-(p-tolylsulfinyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

    Molecular Formula

    C27H31N5OS

    Molecular Weight

    473.65

    Catalogue Number

    AR-T02475

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 24

    Synonym

    3-(4-(((3R,4R)-1-(2-cyanoacetyl)-4-methylpiperidin-3-yl)(methyl)amino)-5H-pyrrolo[2,3-d]pyrimidin-7(6H)-yl)-3-oxopropanenitrile

    Molecular Formula

    C19H23N7O2

    Molecular Weight

    381.44

    Catalogue Number

    AR-T02474

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 23 DiHCl

    Synonym

    N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-amine dihydrochloride

    Molecular Formula

    C13H21N5.2 HCl

    Molecular Weight

    247.35 2 36.46

    Catalogue Number

    AR-T02473

    Parent Drug

    TOFACITINIB

    CAS Number

    1812890-23-5 (free base)
    Tofacitinib Related Compound 21

    Synonym

    3-((3R,4R)-3-((6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile

    Molecular Formula

    C16H22N6O

    Molecular Weight

    314.39

    Catalogue Number

    AR-T02472

    Parent Drug

    TOFACITINIB

    CAS Number

    1640972-35-5
    Tofacitinib Related Compound 20

    Synonym

    3-((3R,4R)-4-methyl-3-(methyl(7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile

    Molecular Formula

    C23H26N6O3S

    Molecular Weight

    466.57

    Catalogue Number

    AR-T02471

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 19

    Synonym

    N-((3R,4R)-1-(2-cyanoacetyl)-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine oxide

    Molecular Formula

    C16H20N6O2

    Molecular Weight

    328.38

    Catalogue Number

    AR-T02470

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 18

    Synonym

    N-((3R,4S)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

    Molecular Formula

    C27H31N5O2S

    Molecular Weight

    489.64

    Catalogue Number

    AR-T02469

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 17

    Synonym

    N-((3S,4R)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

    Molecular Formula

    C27H31N5O2S

    Molecular Weight

    489.64

    Catalogue Number

    AR-T02468

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 16

    Synonym

    N-((3R,4R)-1-ethyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

    Molecular Formula

    C15H23N5

    Molecular Weight

    273.38

    Catalogue Number

    AR-T02467

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 15

    Synonym

    N-methyl-N-((3R,4R)-4-methyl-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-3-yl)acetamide

    Molecular Formula

    C15H21N5O

    Molecular Weight

    287.37

    Catalogue Number

    AR-T02466

    Parent Drug

    TOFACITINIB
    Tofacitinib Related Compound 14

    Synonym

    (3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine-1-carbaldehyde

    Molecular Formula

    C14H19N5O

    Molecular Weight

    273.34

    Catalogue Number

    AR-T02465

    Parent Drug

    TOFACITINIB

    CAS Number

    N/A
    Tofacitinib Related Compound 13

    Synonym

    N-((3R,4S)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

    Molecular Formula

    C20H25N5

    Molecular Weight

    335.46

    Catalogue Number

    AR-T02464

    Parent Drug

    TOFACITINIB

    CAS Number

    N/A
    Tofacitinib Related Compound 12

    Synonym

    N-((3S,4R)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

    Molecular Formula

    C20H25N5

    Molecular Weight

    335.46

    Catalogue Number

    AR-T02463

    Parent Drug

    TOFACITINIB

    CAS Number

    N/A
    Tofacitinib Related Compound 11

    Synonym

    3-((3R,4R)-3-((6-aminopyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile

    Molecular Formula

    C14H20N6O

    Molecular Weight

    288.36

    Catalogue Number

    AR-T02462

    Parent Drug

    TOFACITINIB

    CAS Number

    1640971-60-3
    Tofacitinib Impurity Z

    Synonym

    1-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)ethanone

    Molecular Formula

    C15H21N5O

    Molecular Weight

    287.37

    Catalogue Number

    AR-T02461

    Parent Drug

    TOFACITINIB

    CAS Number

    477600-76-3
    Tofacitinib Impurity Y

    Synonym

    N-((3R,4R)-1,4-dimethylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

    Molecular Formula

    C14H21N5

    Molecular Weight

    259.36

    Catalogue Number

    AR-T02460

    Parent Drug

    TOFACITINIB

    CAS Number

    N/A
    Tofacitinib Impurity X

    Synonym

    (3R,4R)-N,4-dimethyl-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-3-amine

    Molecular Formula

    C13H19N5

    Molecular Weight

    245.33

    Catalogue Number

    AR-T02459

    Parent Drug

    TOFACITINIB

    CAS Number

    N/A
    Tofacitinib Impurity W

    Synonym

    (3R,4R)-1-(2-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-N,4-dimethylpiperidin-3-amine

    Molecular Formula

    C13H18ClN5

    Molecular Weight

    279.77

    Catalogue Number

    AR-T02458

    Parent Drug

    TOFACITINIB

    CAS Number

    N/A