Sacubitril

Desethyl Sacubitril-13C4

Synonym

(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(3-carboxypropanamido)-2-methylpentanoic acid-13C4

Molecular Formula

13C₄ C₁₈H₂₁NO₅

Molecular Weight

383.38

Catalogue Number

AR-S01037

Parent Drug

SACUBITRIL

Desethyl Sacubitril

Synonym

(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(3-carboxypropanamido)-2-methylpentanoic acid

Molecular Formula

C₂₂H₂₅NO₅

Molecular Weight

383.44

Catalogue Number

AR-S01036

Parent Drug

SACUBITRIL

(R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate

Synonym

(R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate

Molecular Formula

C₂₀H₂₅NO₃

Molecular Weight

327.42

Catalogue Number

AR-S01035

Parent Drug

SACUBITRIL

CAS Number

1426129-50-1

(R)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpent-2-enoate hydrochloride

Synonym

(R)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpent-2-enoate hydrochloride

Molecular Formula

C₂₀H₂₃NO₂. HCl

Molecular Weight

309.41 36.46

Catalogue Number

AR-S01034

Parent Drug

SACUBITRIL

(R)-5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpent-2-enoic acid

Synonym

(R)-5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpent-2-enoic acid

Molecular Formula

C₁₈H₁₉NO₂

Molecular Weight

281.36

Catalogue Number

AR-S01033

Parent Drug

SACUBITRIL

(R)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic acid

Synonym

(R)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic acid

Molecular Formula

C₂₃H₂₇NO₄

Molecular Weight

381.47

Catalogue Number

AR-S01032

Parent Drug

SACUBITRIL

(R)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoate

Synonym

(R)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoate

Molecular Formula

C₂₅H₃₁NO₄

Molecular Weight

409.53

Catalogue Number

AR-S01031

Parent Drug

SACUBITRIL

(2R,4S)-isopropyl 5-([1,1'-biphenyl]-4-yl)-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoate

Synonym

(2R,4S)-isopropyl 5-([1,1'-biphenyl]-4-yl)-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoate

Molecular Formula

C₂₅H₂₉NO₄

Molecular Weight

407.51

Catalogue Number

AR-S01030

Parent Drug

SACUBITRIL

4-((3R,5S)-5-([1,1'-biphenyl]-4-ylmethyl)-3-methyl-2-oxopyrrolidin-1-yl)-4-oxobutanoic acid

Synonym

4-((3R,5S)-5-([1,1'-biphenyl]-4-ylmethyl)-3-methyl-2-oxopyrrolidin-1-yl)-4-oxobutanoic acid

Molecular Formula

C₂₂H₂₃NO₄

Molecular Weight

365.43

Catalogue Number

AR-S01029

Parent Drug

SACUBITRIL

(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-(4-ethoxy-4-oxobutanamido)-2-methylpentanoate

Synonym

(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-(4-ethoxy-4-oxobutanamido)-2-methylpentanoate

Molecular Formula

C₂₆H₃₃NO₅

Molecular Weight

439.55

Catalogue Number

AR-S01028

Parent Drug

SACUBITRIL

(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(4-ethoxy-4-oxobutanamido)-2-methylpentanoic acid

Synonym

(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(4-ethoxy-4-oxobutanamido)-2-methylpentanoic acid

Molecular Formula

C₂₄H₂₉NO₅

Molecular Weight

411.50

Catalogue Number

AR-S01027

Parent Drug

SACUBITRIL

(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-(4-isopropoxy-4-oxobutanamido)-2-methylpentanoate

Synonym

(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-(4-isopropoxy-4-oxobutanamido)-2-methylpentanoate

Molecular Formula

C₂₇H₃₅NO₅

Molecular Weight

453.58

Catalogue Number

AR-S01026

Parent Drug

SACUBITRIL

(2R,4S)-isopropyl 5-([1,1'-biphenyl]-4-yl)-4-(4-isopropoxy-4-oxobutanamido)-2-methylpentanoate

Synonym

(2R,4S)-isopropyl 5-([1,1'-biphenyl]-4-yl)-4-(4-isopropoxy-4-oxobutanamido)-2-methylpentanoate

Molecular Formula

C₂₈H₃₇NO₅

Molecular Weight

467.61

Catalogue Number

AR-S01025

Parent Drug

SACUBITRIL

(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(4-isopropoxy-4-oxobutanamido)-2-methylpentanoic acid

Synonym

(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(4-isopropoxy-4-oxobutanamido)-2-methylpentanoic acid

Molecular Formula

C₂₅H₃₁NO₅

Molecular Weight

425.53

Catalogue Number

AR-S01024

Parent Drug

SACUBITRIL

(R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic acid

Synonym

(R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic acid

Molecular Formula

C₂₃H₂₇NO₄

Molecular Weight

381.47

Catalogue Number

AR-S01023

Parent Drug

SACUBITRIL

CAS Number

1015037-46-3

(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoic acid hydrochloride

Synonym

(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoic acid hydrochloride

Molecular Formula

C₁₈H₂₁NO₂. HCl

Molecular Weight

283.37 36.46

Catalogue Number

AR-S01022

Parent Drug

SACUBITRIL

CAS Number

1038924-71-8

(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoate

Synonym

(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoate

Molecular Formula

C₂₅H₃₃NO₄

Molecular Weight

411.55

Catalogue Number

AR-S01021

Parent Drug

SACUBITRIL

Sacubitril Amine-ester Impurity hydrochloride

Synonym

(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate hydrochloride

Molecular Formula

C₂₀H₂₅NO₂. HCl

Molecular Weight

311.43 36.46

Catalogue Number

AR-S01020

Parent Drug

SACUBITRIL

CAS Number

149690-12-0

(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(3-carboxypropanamido)-2-methylpentanoic acid-D4

Synonym

(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(3-carboxypropanamido)-2-methylpentanoic acid-D4

Molecular Formula

C₂₂H₂₁NO₅D₄

Molecular Weight

387.47

Catalogue Number

AR-S01019

Parent Drug

SACUBITRIL

(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid

Synonym

(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid

Molecular Formula

C₂₃H₂₉NO₄

Molecular Weight

383.49

Catalogue Number

AR-S01018

Parent Drug

SACUBITRIL

(2S,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid

Synonym

(2S,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid

Molecular Formula

C₂₃H₂₉NO₄

Molecular Weight

383.49

Catalogue Number

AR-S01017

Parent Drug

SACUBITRIL

(2S,4R)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid

Synonym

(2S,4R)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid

Molecular Formula

C₂₃H₂₉NO₄

Molecular Weight

383.49

Catalogue Number

AR-S01016

Parent Drug

SACUBITRIL

(2R,4R)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid

Synonym

(2R,4R)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid

Molecular Formula

C₂₃H₂₉NO₄

Molecular Weight

383.49

Catalogue Number

AR-S01015

Parent Drug

SACUBITRIL

(2S, 4S)-Sacubitril-d4

Synonym

4-(((2S,4S)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid-D4

Molecular Formula

C₂₄H₂₅NO₅D₄

Molecular Weight

415.53

Catalogue Number

AR-S01014

Parent Drug

SACUBITRIL

Sacubitril-d4

Synonym

4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid-D4

Molecular Formula

C₂₄H₂₅NO₅D₄

Molecular Weight

415.53

Catalogue Number

AR-S01013

Parent Drug

SACUBITRIL

CAS Number

149709-62-6 (non-d)

Desethyl Sacubitril

Synonym

(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(3-carboxypropanamido)-2-methylpentanoic acid

Molecular Formula

C₂₂H₂₅NO₅

Molecular Weight

383.44

Catalogue Number

AR-S01012

Parent Drug

SACUBITRIL

CAS Number

149709-44-4

(3S,5S)-5-([1,1'-biphenyl]-4-ylmethyl)-3-methylpyrrolidin-2-one

Synonym

(3S,5S)-5-([1,1'-biphenyl]-4-ylmethyl)-3-methylpyrrolidin-2-one

Molecular Formula

C₁₈H₁₉NO

Molecular Weight

265.36

Catalogue Number

AR-S01011

Parent Drug

SACUBITRIL

CAS Number

1038925-00-6

2,5-Dioxopyrrolidine Sacubitril

Synonym

(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoate

Molecular Formula

C₂₄H₂₇NO₄

Molecular Weight

393.48

Catalogue Number

AR-S01010

Parent Drug

SACUBITRIL

CAS Number

1038924-97-8

Sacubitril Cyclic Impurity

Synonym

(3R,5S)-5-([1,1'-biphenyl]-4-ylmethyl)-3-methylpyrrolidin-2-one

Molecular Formula

C₁₈H₁₉NO

Molecular Weight

265.36

Catalogue Number

AR-S01009

Parent Drug

SACUBITRIL

CAS Number

1038924-70-7

Sacubitril-(2S,4S)-Isomer

Synonym

4-(((2S,4S)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid

Molecular Formula

C₂₄H₂₉NO₅

Molecular Weight

411.50

Catalogue Number

AR-S01007

Parent Drug

SACUBITRIL

CAS Number

149709-63-7

Sacubitril-(2R,4R)-Isomer

Synonym

4-(((2R,4R)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid

Molecular Formula

C₂₄H₂₉NO₅

Molecular Weight

411.50

Catalogue Number

AR-S01006

Parent Drug

SACUBITRIL

Sacubitril Enantiomer

Synonym

4-(((2R,4S)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid

Molecular Formula

C₂₄H₂₉NO₅

Molecular Weight

411.50

Catalogue Number

AR-S01005

Parent Drug

SACUBITRIL

CAS Number

761373-05-1

Sacubitril

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